Labthink Knowledge

Sterile Barrier System (SBS) is the minimum package that prevents the ingress of microorganisms and allows aseptic presentation of the product at the point of use. To maintain the highest levels of safety, manufacturers are increasingly turning to advanced instrumentation like the Labthink C660B and C660M to validate and monitor their packaging performance. This article explores how a dual-testing approach, combining qualitative leak detection with quantitative seal strength analysis, provides the rigorous data required for ISO 11607 compliance. The Integrity Challenge: Why Leak and Seal Strength Tests Matter ？ A Sterile Barrier System must remain intact from the point of sterilization until it is opened by a healthcare professional. However, flexible medical packaging faces numerous risks during its lifecycle, including pressure changes during air transport, mechanical shocks during shipping, and compression in storage. Re...

ProPak Asia is Asia's Number One international trade event for Processing & Packaging Technology. ProPak Asia truly is the "Must-Attend" industry event in Asia for Asia, as quality and variety of products increase and expand, and productivity of operations and manufacturing standards are driven higher by consumer demands and new automation and technological advances, which will be presented at the show. As Asia's Number One international trade event for processing & packaging trade event for food, drink, pharmaceutical, cosmetics, and consumer products, ProPak brings together exhibiting companies and buyers from around the world. The exhibition is the center stage for market trend, industry & investment networking, and environmental discussion. Labthink is heading to PROPAK ASIA 2025! 📍 Booth AE64, BITEC Bangkok 📅 June 11–14, 2025 Discover our latest innovations in packaging quality control, including solutions for leak detection, permeation testing, and...

Container Closure Integrity (CCI) testing is performed within the pharmaceutical, biotech, and food and beverage industries, primarily to ensure product sterility and prevent contamination, maintain product quality and stability, identify packaging defects, and meet regulatory requirements. Regulatory bodies like the FDA (in the United States) and similar agencies worldwide have stringent requirements for container closure systems, particularly for sterile and pharmaceutical products. These regulations mandate that manufacturers demonstrate the integrity of their packaging to ensure product safety and efficacy. There are various instruments used for Container Closure Integrity (CCI) testing, employing different methods to detect leaks. Such as vacuum decay testers, pressure decay testers, High Voltage Leak Detection (HVLD) instruments, and mass extraction leak detectors, these instruments employ deterministic methods which provide quantitative, objective results. Probabilistic methods ...